The Advisory Committee on Immunization Practices currently recommends that infants and children 9-years-old and younger receive two doses of H1N1 vaccine at least 21 days apart. The regimen was chosen based on the current recommended course for seasonal flu.
But Terry Nolan, a researcher with the University of Melbourne, Australia, said he and his colleagues conducted a randomized study involving 370 healthy infants and children between the ages of 6 months and 9 years. The children received two injections of H1N1 vaccine 21 days apart. One group was given a 15-micrograms injection and the other a 30-microgram injection.
Nolan said in a statement that a single 15-microgram dose may be effective and well-tolerated in children.
The study is published in the online edition of the Journal of the American Medical Association
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